Sunday, 13 July 2014

The 5th international online veterinary conference: July 2014


Vet Education provides the highest quality online continuing education to veterinarians, veterinary nurses/technicians and support staff. Whether it be one of our highly interactive distance-learning courses, or our outstanding acclaimed webinar series, we have the right CPD choice for you!
Distance-Learning Courses: Join one of our immersive interactive online courses and find out why our courses are consistently praised by our students! Featuring live online tutorials, printed and bound course notes, interactive exercises, useful practice resources, comprehensive assessment and a whole lot more!

Complete with our own virtual event centre, our 5th annual online veterinary conference features 16 webinars delivered by some of the world’s most sought-after veterinary speakers, including Dr Stephen Di Bartola (fluid therapy), Dr Claire Rusbridge (neurology), Dr Rob Stein (analgesia), Dr Amanda Burrows (dermatology) and many more!

For details click  HERE

Saturday, 5 July 2014

Surrey Vet school embarks on Dachshund movement study

Surrey researchers use technology and techniques developed to improve human health to help dogs with paralysis and other neurological problems.

Working with the Department of Mechanical Engineering Sciences, researchers from the School of Veterinary Medicine will analyse the patter of 120 paws belonging to 30 healthy smooth, long and wire haired miniature Dachshunds . The study is taking place in Surrey’s Biomedical Engineering Gait Analysis Laboratory, usually reserved for human subjects. 

Using a 3D motion capture camera system, a pressure mat and a force plate, researchers will measure the dogs’ stability while standing and monitor how their back and limbs move during walking. Some of the dogs will be kitted out in 24 tiny reflective markers, so motion cameras can capture their movements as a 3D computer model. Researchers hope to develop a system to score the dogs’ core muscle stability, similar to the one used for humans following a stroke.The study's results will help vets to get an objective picture of what healthy dog core stability looks like so they can make evidence-based decisions about the rehabilitation of dogs that are unwell.

Study leader Dr Constanza Gómez Álvarez, Lecturer in Musculoskeletal Biology, said,
“The data will help us to investigate new forms of rehabilitation, for example low level laser therapy, with the aim of shortening recovery times. Currently, vets rely on clinical examination and neurological indicators to evaluate the recovery of dogs paralysed by intervertebral disc disease. We hope to establish an objective score for healthy core stability, so we can make an unbiased analysis of patients and tailor rehabilitation methods accordingly. We also hope to improve the understanding of how this breed moves and why these dogs suffer from back problems.”

The research team includes Dr Aliah Shaheen, Lecturer in Human Movement Analysis and Dr Clare Rusbridge, Reader in Veterinary Neurology and Chief of Neurology at Fitzpatrick Referrals, where part of the study is taking place.


Well done Dachshund Breed Club for supporting this initiative which will help all breeds with back problems

Tuesday, 10 June 2014

Cavalier Matters Charity promotes research to provide objective grading of Chiari Malformation in Cavaliers



Cavalier Matters is funding a PhD project at the University of Surrey to quantify Chiari-like Malformation (CM) and Syringomyelia (SM) in the Cavalier King Charles Spaniel.


This research project seeks to provide objective measurements on an Magnetic Resonance Image (MRI) for both CM and SM affectedness that can better assess the degree of risk for inheriting both these conditions.  The funding will enable Susan P. Knowler (Penny) to extend the genetic research recently announced supported by the Dogs Trust. It is hoped that any gene/genomic markers identified in the cavalier breed will strengthen the development of Estimated Breeding Values (EBVs) and provide a powerful screening tool for breeders.  

Supported by cavalier lovers worldwide, Penny has been investigating the inheritance and phenotype of CM and SM in Cavaliers and other breeds for over a decade. The project carries forward the research undertaken with Dr Clare Rusbridge, Head of Neurology at Fitzpatrick Referrals and Reader in Neurology at Surrey University.  The senior supervisor for the project is Prof Roberto La Ragione

Saturday, 3 May 2014

Dr Colin Driver awarded PhD from the University of Ghent for his research into Syringomyelia secondary to Chiari-like malformation


Many congratulations  to Dr Colin Driver on his award of a PhD from the University of Gent and his thesis "New Insights into the Pathogenesis of Syringomyelia secondary to Chiari-like malformation in dogs". This considerable body of work is the culmination of ~ 7 years hard work and Dr Driver has made a pivotal contribution to the dog and scientific community's understanding of this enigmatic disease.  May he go from strength to strength


Tuesday, 29 April 2014

Dogs Trust to fund the search for gene/s for Syringomyelia and painful Chiari-Malformation in Cavaliers.

Dogs Trust Canine Welfare have awarded University of Surrey a grant of over £138,500 to fund the  ‘Identification of gene(s) predisposing to syringomyelia associated with Chiari-like malformation in the Cavalier King Charles.  



Dogs Trust wish to stress that the fundamental aim of all grants submitted must be centred on a solutions-based approach to conditions in dogs with a genetic underpinning and serious welfare implications.

Dr Clare Rusbridge, Reader in Neurology, will head up the research in collaboration with Dr Zoha Kibar in Montreal University CHUM research centre. It follows the success that identified two novel genomic regions in the Griffon Bruxellous breed. (see paper


The team used an approach called Qualitative Trait Locus (QTL) analysis which involved linking two types of information – phenotypic data (trait measurements) and genotypic data (usually molecular markers) in an attempt to explain the genetic basis of variation. (see paper) The research is not invasive and does not require a Home Office licence. The new funding will allow this powerful technique to be repeated in the Cavalier King Charles spaniel breed with a view to finding a genetic cause for both painful CM and Syringomeylia. Not only may it help dogs and breeders, but it might also help improve understanding of the condition in humans and lead to improved diagnosis and treatment options.”

Thank you so much Dogs Trust on behalf of cavalier lovers worldwide

Monday, 28 April 2014

APBC 'Behaviour Essentials' Day




Association of Pet Behaviour Counsellors

Thursday, 5 June 2014 from 10:00 to 16:00 (BST)

Coventry, United Kingdom

Click HERE for more details and registration


Understanding and managing behavioural impact of pain, client expectations and management during peri-operative periods. Keeping up-to-date with issues in companion animal behaviour will have a beneficial effect on your veterinary practice, for staff, clients and the pets themselves.  This one day conference, aimed at veterinary surgeons and veterinary nurses, includes four leading and popular speakers and will help you and your colleagues remain 'behaviourally aware'.  

Speakers and their Subjects
 




Tamsin Durston

Physical examination – A ‘Hands-Off’ Approach (a behavioural approach to minimising patient stress within the veterinary consultation)




Clare Rusbridge BVMS PhD DipECVN MRCVSRCVS and European Specialist in Veterinary Neurology 
Pain and Behaviour 1: The Pain Brain - neurobiology of pain 

                                                                                
Sarah Heath






Sarah Heath BVSc DipECVBM-CA MRCVS

Pain and Behaviour 2: The interplay between pain and behaviour

Wednesday, 16 April 2014

Candidate gene for Chiari malformation in dogs identified in the Griffon Bruxellois.


Quantitative trait loci (QTL) study identifies novel genomic regions associated to Chiari-Like Malformation in Griffon Bruxellois dogs

Philipe Lemay,1 Susan P. Knowler,2 Samir Bouasker,1 Yohann Nédélec,1 Simon Platt,3 Courtenay Freeman,3 Georgina Child,4 Luis B. Barreiro,1 Guy A. Rouleau,5 Clare Rusbridge 2,6 and Zoha Kibar1,
1CHU Sainte Justine Research Center and University of Montréal, 2 Fitzpatrick Referrals, Halfway Lane, Eashing, Godalming, Surrey, GU7 2QQ, 3 Department of Small Animal Medicine & Surgery, College of Veterinary Medicine, University of Georgia, 4 Small Animal Specialist Hospital, 1 Richardson Place North Ryde NSW 2113, Australia, 5 Montreal Neurological Institute and McGill University 6 School of Veterinary Medicine, Faculty of Health & Medical Sciences, Surrey, UK

We are excited and delighted to announce after four years hard work collecting DNA from Griffon Bruxellois from dedicated owners and worldwide, the genetics group headed by Dr Zoha Kibar at Sainte Justine Hospital Research Center and University of Montreal identified two DNA regions that were strongly associated with Chiari-like malformation in the dog.  They used a quantitative trait locus (QTL) approach that linked DNA molecular markers with magnetic resonance imaging information gleaned by researcher Penny Knowler and neurologist Dr Clare Rusbridge (see here) This identified two novel genomic regions involved in development of the skull and has been associated with a disease linked to Chiari malformation in humans. The team is very excited by this finding because not only may it help dogs and breeders but it might help understand the condition in humans.

The research was published in the journal PLOS ONE: http://dx.plos.org/10.1371/journal.pone.0089816

To investigate the genetic complexity of the disease, a total of 14 quantitative skull and atlas measurements were taken and were tested for association to CM.  Seven traits were found to be associated to CM and were subjected to a whole-genome association study.  One of the two genomic region identified contains an excellent candidate gene called Sall-1 since its equivalent in humans is is mutated in Townes-Brocks syndrome which has previously been associated to CMI.  The dog model is the only known naturally-occurring animal model for CMI in humans.  Hence, gene identification studies in CM in the dog might provide an entry point for identification of novel genes and pathways involved in the pathogenesis of CMI in humans.


See the changes in the shape of the Griffon head with SM -here (u-tube looks blank at start)